Maximize Yield in Pharmaceutical Manufacturing Utilizing Thf′s Exceptional Solvating Abilities

• CAS No.: 109 99 9
• Formula: C4h8o
• EINECS: 203-786-5
• Model NO.: THF
• Type: Amphiprotic Solvent
• Composition: Inorganic
• Usage: Dissolved, Medium, Bonding
• Flux Type: Basic Flux
• Molecular Weight: 72.107
• CAS: 109 99 9
• Melting Point: -108.5 °c
• Boiling Point: 66 °c
• Water Solubility: Soluble
• Density: 0.89 G/Cm³
• Appearance: Colorless Transparent Liquid
• Flash Point: -14 °c (Cc)
• Safety Description: S16; S26; S29; S33; S36
• Hazard Symbol: F
• Hazard Description: R11; R19; R36/37
• Un Dangerous Goods Number: 2924
• Transport Package: Drum
• Specification: 180kg/drum
• Origin: China
• HS Code: 29321100
• Production Capacity: 50000 Pieces/Year

Product Description

Product Description

 

safety/security information
CAS	109/99/9
EINECS	203-786-5
Chemical formula	C4H8O
Molecular weight	72.107
Melting point	-108.5 °C
Boiling point	66 °C
Water solubility	soluble
Density	0.89 g/cm³
Appearance	colorless transparent liquid
Flash point	-14 °C (CC)
Safety description	S16; S26; S29; S33; S36

THF) is a cyclic ether. It is a colorless liquid with low viscosity and miscible with water at room temperature and pressure. Its chemical formula can be written as (CH2)4O. Due to its long liquid range, it is a commonly used medium polar aprotic solvent. Its main use is as a precursor of high molecular polymers.
THF is produced in quantities of about 200,000 tonnes per year. [2] The most widely used method is the acid-catalyzed dehydration , similar to the dehydration of ethanol to produce ethylene. Butanediol can be obtained by carbonylation of acetylene followed by hydrogenation. DuPont has developed a method for producing by oxidation followed by catalytic hydrogenation. [3] Butanediol can also be produced by hydroformylation followed by hydrogenation.

THF can also be produced by catalytic hydrogenation of f. .F can be derived from pentose sugars. However, this method is not widely used.
THF can be polymerized into chain-like polytetramethylene oxide (PTMEG) in a strong acidic environment. CAS No. [25190-06-1], also known as PTMO, which stands for "polytetramethylene oxide". Its basic use is to make elastic polyurethane fibers, such as spandex.