| safety/security information |
| Dangerous goods sign |
C,N |
| Hazard category code |
34-50/53-14-36/37 |
| Safety instructions |
26-36/37/39-45-61-27 |
| Dangerous goods transport number |
UN 3261 8/PG 3 |
| WGK Germany |
3 |
| RTECS none |
PA6450000 |
| F |
10-19-21 |
| Hazard Note |
Irritant |
| TSCA |
Yes |
| danger classes |
8 |
| Packaging category |
III |
| Customs code |
29036990 |
| Toxic substance data |
76-83-5(Hazardous Substances Data) |
| toxicity |
LD50 orally in Rabbit: > 5000 mg/kg |
Triphenylmethyl chloride is white-like crystal, insoluble in water, easily soluble in benzene, carbon disulfide and petroleum ether, slightly soluble in alcohol and ether, and becomes triphenyl alcohol after water absorption; Melting point of chemical book is 110ºC ~ 112ºC, and boiling point is 230ºC ~ 235ºC (20mmhg). It is an important pharmaceutical intermediate and one of the basic organic raw materials commonly used in pharmaceutical and chemical fields.
Triphenylmethyl chloride is one of the basic organic raw materials commonly used in the field of medicine and chemical engineering. In the process of organic chemical engineering and drug synthesis, it can be used as a selective protective group for primary hydroxyl groups, amino groups and sulfhydryl groups in compounds such as nucleoside, monosaccharide or polysaccharide, and as a basic chemical reagent in polypeptide synthesis. Triphenylmethyl chloride is used as a protective reagent in the process of organic chemical engineering and drug synthesis, and in the process of removing triphenylmethyl protective group in acidic alcohol solution, triphenylmethyl alkyl ether such as triphenylmethyl ether, triphenylmethyl ethyl ether, triphenylmethyl propyl ether and other by-products are usually generated.
use:
1. It is used as an intermediate of cephalosporins to synthesize antiviral drug iodine glycoside. 2, used as amino protective reagent. 3, used as initiator of resin polymer, catalyst of organic reaction, flour improver, fiber decolorant and rubber product exchanger, and also used in the production of medicine and pesticide. 4. Triphenylmethyl chloride is one of the basic organic raw materials commonly used in the field of medicine and chemical industry. It can be used as a selective protective group for primary hydroxyl groups in compounds such as nucleoside, monosaccharide or polysaccharide, and as a basic chemical reagent in polypeptide synthesis. 5. Test the primary alcohol in sugar. Organic synthesis. Triphenylmethylation agent, used for group protection of amines, alcohols and thiols. Used in Wittig reaction to form onium salt. 6, triphenylmethyl reagent
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